Drug intelligence / Profile preview

sulfated alfalfa polysaccharide

Development stage
Preclinical
Administration
Oral
01

Overview

Sulfated alfalfa polysaccharide is a chemically sulfated polysaccharide preparation derived from alfalfa and studied as a bioactive natural product for obesity-related metabolic modulation. In the provided publication context, it is not described as a conventional pharmaceutical development candidate with a named sponsor, but as a modified plant polysaccharide that alleviated obesity-associated intestinal inflammation and gut dysbiosis in experimental research. Reported effects included downregulation of colonic inflammatory genes such as COX-2, PepT-1, and HK2, upregulation of TPH1, normalization of intestinal pH and growth, shifts in gut microbiota including increased Dubosiella and Fecalibaculum, and metabolic effects enriched in amino acid metabolism pathways. The evidence provided supports classification as a sulfated plant-derived nutraceutical or research bioactive rather than an approved drug product.

Other names
sulfated alfalfa polysaccharidesulfated alfalfa polysaccharidesSAP

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