Drug intelligence / Profile preview

sulisobenzone

Development stage
Unknown
Lead developer
BioPhausia
Modality
Small Molecules
Administration
Topical
01

Overview

Sulisobenzone is an organic compound belonging to the benzophenones class, primarily used as a sunscreen agent. It functions as a UV filter, absorbing both UVA and UVB radiation to protect the skin from sun-induced damage such as sunburn, premature aging, and increased risk of skin cancer. The mechanism involves chemical absorption of ultraviolet light energy by the molecule’s conjugated system; this energy is then dissipated harmlessly as thermal energy when the molecule returns to its ground state. Sulisobenzone is approved for use in concentrations up to 10% in topical formulations by regulatory agencies such as the FDA and Health Canada. It does not significantly penetrate human skin but may enhance penetration of other chemicals. Sulisobenzone is widely used in sunscreens and personal care products[1][2][3][6]. Some sources refer to potential for mild skin or eye irritation with use; there are also ongoing studies regarding possible endocrine-disrupting effects, though evidence remains limited[4][6]. No specific developer or manufacturer names were identified in available sources.

Brand names
BENEFIT TRIPLE PERFORMING FACIAL BROAD SPECTRUM SPF15
Other names
5-benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid2-hydroxy-4-methoxybenzophenone-5-sulfonic acidsulisobenzone

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