sulpiride

Sulpiride is a benzamide derivative antipsychotic medication primarily used for the treatment of acute and chronic schizophrenia. It acts as a selective antagonist at dopamine D2 and D3 receptors in the brain, with some activity at D4 receptors at higher doses. This mechanism reduces dopaminergic neurotransmission associated with psychotic symptoms. At low doses, sulpiride may also exhibit antidepressant effects due to its action on presynaptic dopamine and serotonin receptors. Sulpiride is not approved by the FDA or EMA but is marketed in several countries under various brand names for psychiatric indications including schizophrenia and certain anxiety disorders[1][2][4][5]. Developed by Sanofi.

Brand names

DogmatilDolmatilEglonylEspirideModalSulpor

Other names

Sulpirid