sultamicillin

**Sultamicillin** is an orally administered mutual prodrug of the aminopenicillin antibiotic ampicillin and the beta-lactamase inhibitor sulbactam. Following absorption, it releases ampicillin, which binds bacterial penicillin-binding proteins and inhibits peptidoglycan cross-linking and cell-wall synthesis, and sulbactam, which irreversibly inhibits susceptible bacterial beta-lactamases and protects ampicillin from enzymatic degradation. It is used for susceptible bacterial infections, including respiratory-tract, urinary-tract, skin and soft-tissue, and gonococcal infections. Pfizer originated and marketed oral sultamicillin as Unasyn in multiple markets.

Brand names

AMPIUMAmpibactamAmpibactam SAmpigen SBAmpimaxAmplipenAprid FVBactesulBactesynBegalinBitammon BBCaderynCinamFipexiamMeinuoxianPentrexyl-S12-HPentrexyl-S-12-HPentrexyl-S 12-HPensilinaPicynSaltumSulampSulcidSultabestSultamatSultamixSultibacUnacid PDUnasynUnasyn 375 mgUnasyn375 mgUnasyn-375 mgUnasyn BBUnasyn OralUnathenVasentoxilViccillin-SX

Other names

sultamicillinesultamicillinasultamicillini tosilas dihydricussultamicillinumsultamicillin tosilate dihydratesultamicillin tosilate hydrate