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SUN-907 is an orally bioavailable small molecule inhibitor of Tyrosine Kinase 2 (TYK2) being developed by Sundance Biosciences. TYK2 is a member of the Janus kinase (JAK) family that mediates signaling for several key cytokines involved in inflammatory and immune responses, including IL-12, IL-23, and Type I interferons. By selectively targeting TYK2, SUN-907 aims to modulate neuroinflammatory pathways while potentially avoiding the off-target effects associated with broader JAK inhibitors. The program is currently in the IND-enabling stage, with a primary focus on treating neuroinflammatory conditions.
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