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SUN11031 is a fully synthetic analog of the human ghrelin hormone. It was originally developed for the treatment of muscle wasting (cachexia) and appetite disorders associated with chronic diseases such as chronic obstructive pulmonary disease (COPD). More recently, it has been acquired by Oxeia Biopharmaceuticals and is being developed under the code name OXE-103 for the treatment of concussion and other acute neurotrauma. Ghrelin is a peptide hormone known for its pleiotropic neuroprotective properties, including effects on appetite regulation, muscle mass preservation, and potential benefits in brain injury recovery. SUN11031 has demonstrated a strong safety profile across nine clinical studies involving 345 patients[2][3][9].
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