Drug intelligence / Profile preview

Suncoril

Development stage
Unknown
Lead developer
Sunlife
Modality
Small Molecules
Administration
Oral
01

Overview

Suncoril (also known as Suncoril Expectorant) is a fixed-dose combination syrup developed by Sunlife Pharmaceuticals for the treatment of cough and respiratory conditions associated with bronchospasm and viscid mucus. The formulation contains four active ingredients: terbutaline (a selective beta-2 adrenergic receptor agonist that acts as a bronchodilator), ambroxol (a mucolytic agent that thins and loosens phlegm), guaifenesin (an expectorant that increases the volume and reduces the viscosity of respiratory tract secretions), and menthol (which provides a cooling sensation and local anesthetic effect via TRPM8 activation). Together, these components work synergistically to relieve chest congestion, facilitate expectoration, and ease breathing.

Brand names
SuncorilSuncoril Expectorant
Other names
Suncoril Syrupambroxol + guaifenesin + menthol + terbutalineambroxol + guaiphenesin + menthol + terbutaline
02

Targets

ADRB2 (β2)GBA1 (Glucosylceramidase)GBA2 (Beta-glucosidase 2)SCN10A (Sodium channel protein type X alpha subunit)TRPM8 (Transient receptor potential cation channel subfamily M member 8)

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