Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
SupCBAKK
- Development stage
- Preclinical
- Modality
- Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
SupCBAKK is a postbiotic formulation consisting of the mixed fermented metabolites (supernatants) derived from the probiotics *Clostridium butyricum* (CB) and *Akkermansia muciniphila* (AKK). It is being investigated as a therapeutic intervention for inflammatory bowel disease (IBD) and colorectal cancer (CRC). SupCBAKK functions through a multi-targeted approach by modulating immune responses, repairing the intestinal mucosal barrier, and ameliorating gut dysbiosis. Preclinical research indicates that this combination of metabolites exhibits significant synergistic effects compared to individual components and can enhance the efficacy of immune checkpoint inhibitors, such as anti-PD-L1, by increasing tumor sensitivity to immunotherapy and amplifying antitumor immune responses.
- Other names
- mixed fermented metabolites of Clostridium butyricum and Akkermansia muciniphilaSupCB + SupAKK
Beyond the preview
Go deeper on SupCBAKK.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on SupCBAKK.