Drug intelligence / Profile preview

SuperCitrimax

Development stage
Unknown
Lead developer
Lonza
Modality
Small Molecules
Administration
Oral
01

Overview

SuperCitrimax (HCA-SX) is a patented, water-soluble calcium/potassium salt of (-)-hydroxycitric acid (HCA) derived from the dried fruit rind of *Garcinia cambogia*. Unlike simple calcium salts of HCA, the double-salt configuration of SuperCitrimax is designed for enhanced solubility, bioavailability, and absorption. Its primary mechanism of action is the competitive inhibition of ATP citrate lyase, the enzyme responsible for converting citrate into acetyl-CoA, which is a critical step in de novo lipogenesis (fatty acid synthesis). By inhibiting this pathway, SuperCitrimax reduces fat production and promotes glycogen synthesis in the liver, which may signal satiety to the brain via the vagus nerve. Clinical research also suggests that SuperCitrimax may increase synaptic serotonin levels, further contributing to appetite suppression and reduced food intake. It is widely used as an ingredient in dietary supplements for weight management and metabolic health.

Brand names
SuperCitrimax
Other names
Super CitriMaxhydroxycitric acid-SX(-)-hydroxycitric acid calcium/potassium salt
02

Targets

ACLY (ATP-citrate synthase)

Beyond the preview

Go deeper on SuperCitrimax.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on SuperCitrimax.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call