Drug intelligence / Profile preview

superoxide dismutase

Development stage
Phase 2
Lead developer
Biogen
Modality
Therapeutic Enzymes → Recombinant Proteins and Enzymes
Administration
Oral, Injectable, Topical
01

Overview

Superoxide dismutase (SOD) is an enzyme found in all living cells that catalyzes the conversion of superoxide radicals into hydrogen peroxide and molecular oxygen, playing a critical role in the body's antioxidant defense system. It helps protect cells from oxidative damage by neutralizing potentially harmful oxygen molecules. SOD exists in several forms including copper-zinc SOD, manganese SOD, iron SOD, and nickel SOD, distributed throughout different cellular compartments. The enzyme has been investigated for its anti-inflammatory and antioxidant properties in various conditions including osteoarthritis, rheumatoid arthritis, and idiopathic pulmonary fibrosis.

Brand names
OrgoteinPalosein
Other names
SODCu/Zn SODFe SODMn SODMetalloproteinSuperóxido DismutasaSuperoxydase DismutaseSuperoxyde Dismutase

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