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SUPLINEURO

Development stage
Unknown
Lead developer
Neurogenics Therapeutics
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

SUPLINEURO is a multi-ingredient neuro-supportive formulation developed by Neurogenics Therapeutics, primarily used for the management of peripheral and diabetic neuropathies. It combines Methylcobalamin, Alpha Lipoic Acid, Pyridoxine, and Folic Acid to address nerve damage and nutritional deficiencies. Methylcobalamin, a bioactive form of Vitamin B12, facilitates the synthesis of the myelin sheath and promotes axonal regeneration. Alpha Lipoic Acid serves as a potent antioxidant that neutralizes reactive oxygen species, thereby reducing oxidative stress-induced nerve injury and improving endoneurial blood flow. Pyridoxine and Folic Acid support essential metabolic pathways, including homocysteine regulation and neurotransmitter synthesis, which are critical for maintaining optimal neurological function.

Brand names
SUPLINEURO
Other names
SUPLINEURO-Neurogenics
02

Targets

MTR (Methionine synthase)PDXK (Pyridoxal kinase)DHFR (Dihydrofolate reductase)

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