Drug intelligence / Profile preview

Suplineuro Plus

Development stage
Unknown
Lead developer
Neurogenics Therapeutics
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

Suplineuro Plus is a multi-ingredient nutraceutical formulation developed by Neurogenics Therapeutics, specifically designed to support nerve health and manage symptoms associated with peripheral neuropathy, including diabetic neuropathy. The product combines high-dose methylcobalamin (Vitamin B12), alpha-lipoic acid, pyridoxine (Vitamin B6), and folic acid. Methylcobalamin acts as a vital cofactor for methionine synthase, which is essential for the synthesis of the myelin sheath and nerve regeneration. Alpha-lipoic acid serves as a potent antioxidant that neutralizes free radicals, improves endoneurial blood flow, and reduces oxidative stress-induced nerve damage. Pyridoxine and folic acid provide critical metabolic support for neurotransmitter synthesis and cellular repair. Together, these components work synergistically to alleviate neuropathic symptoms such as numbness, tingling, and burning sensations.

Brand names
Suplineuro Plus
02

Targets

MTR (Methionine synthase)CBS (Cystathionine beta-synthase)DHFR (Dihydrofolate reductase)

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