Drug intelligence / Profile preview

Suprimun

Development stage
Unknown
Lead developer
Amega Biotech
Modality
Small Molecules
Administration
Oral
01

Overview

Suprimun is an immunosuppressant small molecule developed and marketed by Amega Biotech. It is a prodrug of mycophenolic acid (MPA), which acts by inhibiting inosine monophosphate dehydrogenase (IMPDH). This inhibition leads to the depletion of guanine nucleotides, which are essential for DNA synthesis in T and B lymphocytes, thereby suppressing their proliferation. Suprimun is indicated for the prophylaxis of acute organ rejection in patients receiving allogeneic kidney, heart, or liver transplants, typically used in combination with cyclosporine and corticosteroids.

Brand names
Suprimun
Other names
mycophenolate mofetil
02

Targets

IMPDH (Inosine-5'-monophosphate dehydrogenase 1)

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