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Surface Pre-Reacted Glass (S-PRG) fillers are bioactive glass fillers incorporated into various dental materials, such as resin composites, varnishes, and sealants. These fillers are designed to release multiple therapeutic ions, including fluoride, strontium, boron, sodium, aluminum, and silicon. The released ions contribute to the remineralization of tooth enamel and dentin, neutralize acids produced by cariogenic bacteria, and exhibit antibacterial properties. This technology is utilized in products like PRG Barrier Coat for applications such as caries prevention, treatment of white spot lesions, and management of dentin hypersensitivity. SHOFU Inc. is a developer and manufacturer of products utilizing S-PRG technology.
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