Drug intelligence / Profile preview

Surgiflo

Development stage
Phase 1
Lead developer
Ethicon
Modality
Recombinant Proteins and Enzymes
Administration
Topical
01

Overview

Surgiflo is a flowable hemostatic matrix composed of porcine-derived gelatin and human-derived thrombin. It is designed to provide a physical scaffold for clot formation while actively promoting the coagulation cascade through the enzymatic action of thrombin, which converts fibrinogen into fibrin. Developed and manufactured by Ethicon (a Johnson & Johnson company), Surgiflo is primarily used in surgical settings to control bleeding (hemostasis) when conventional techniques like ligation or cautery are ineffective or impractical. It is frequently utilized in orthopedic, vascular, and general surgery to reduce perioperative and postoperative blood loss.

Brand names
Surgiflo
Other names
Surgiflo Hemostatic Matrix

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