Drug intelligence / Profile preview

Surgiflo

Development stage
Unknown
Lead developer
Ethicon
Modality
Recombinant Proteins and Enzymes, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Device-based Delivery → Drug Delivery Systems
Administration
Topical
01

Overview

Surgiflo is a topical absorbable hemostatic agent used as an adjunct to hemostasis in surgical procedures when conventional methods (such as ligature or pressure) are ineffective or impractical. It consists of a flowable gelatin matrix made from porcine gelatin, which can be mixed with sterile saline or thrombin solution. When applied to bleeding surfaces, the matrix provides a scaffold for platelet adherence and aggregation, accelerating the formation of a platelet plug and aiding in fibrin clot formation. The product is fully absorbed within 4–6 weeks after application. Its primary mechanism is mechanical tamponade and facilitation of the body's natural coagulation cascade[1][6][7][8]. Developed for use in various types of surgery (except ophthalmic), it is not intended for intravascular use or closure of skin incisions due to risk of complications such as embolization or interference with wound healing[6].

Brand names
Surgiflo
Other names
Surgiflo Hemostatic MatrixSURGIFLO Hemostatic Matrix Kit
02

Targets

F (Coagulation factors)

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