survivin messenger RNA vaccine

A **survivin messenger RNA vaccine** is an investigational therapeutic cancer vaccine approach in which messenger RNA encodes survivin, a tumor-associated antigen also known as baculoviral IAP repeat-containing protein 5. Available public descriptions identify it as an mRNA vaccine encoding a **double-mutant variant survivin polypeptide** intended to induce anti-tumor immune responses against survivin-expressing malignant cells, with multiple myeloma specifically cited as an example indication. The concept is distinct from peptide survivin vaccines such as SurVaxM and from dendritic-cell or adenoviral survivin vaccines; based on publicly accessible source material, the exact clinical product identity, formulation details, delivery system, and sponsoring company for a specific drug candidate called simply \"survivin messenger RNA vaccine\" are not clearly established.

Other names

survivin mRNA vaccinevariant survivin mRNA vaccine