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SVS20
- Development stage
- Unknown
- Lead developer
- TRB Chemedica
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Ophthalmic
01
Overview
SVS20 is an investigational ophthalmic formulation developed by TRB Chemedica International SA for the treatment of dry eye syndrome (DED). It is a sodium hyaluronate-based solution that functions as a lubricant and ocular surface protectant. By coating the ocular surface, it mimics the viscoelastic properties of natural tears to stabilize the tear film and relieve symptoms such as dryness, burning, and irritation. SVS20 has been evaluated in Phase II clinical trials as an active comparator against standard treatments like carbomer and saline, as well as in non-inferiority studies against other ophthalmic formulations. It is part of TRB Chemedica's established expertise in hyaluronic acid-based products, which are typically marketed under the VISMED brand line.
- Brand names
- VISMED
- Other names
- sodium hyaluronate ophthalmic solution
02
Targets
CD44 (CD44 antigen)
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