Drug intelligence / Profile preview

swertia chirayata extract

Development stage
Unknown
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral, Topical
01

Overview

Swertia chirayata extract is a botanical extract derived from the medicinal plant *Swertia chirayata* (also known as *Swertia chirayita*), native to the temperate Himalayas. It is a traditional herbal remedy widely used in Ayurvedic, Unani, and other indigenous medical systems. The extract contains a diverse array of bioactive phytochemicals, including xanthones (such as mangiferin and swerchirin), iridoid glycosides (such as amarogentin and swertiamarin), flavonoids, and terpenoids. It exhibits a broad spectrum of pharmacological activities, including antidiabetic, anti-inflammatory, antioxidant, hepatoprotective, antimicrobial, and antimalarial properties. Traditionally, it has been utilized to treat fever, malaria, diabetes, gastrointestinal disorders, and skin diseases.

Other names
chirata extractchirayata extractkiratatikta extractswertia chirata extractswertia chirayita extract
02

Targets

TOP1 (DNA Topoisomerase I)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TAS2R (Taste receptor type 2 family)AMY (Pancreatic alpha-amylase)Sucrase-Isomaltase

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