Drug intelligence / Profile preview

SY-12696

Development stage
Unknown
Lead developer
Shouyao Holdings
Modality
Small Molecules
01

Overview

SY-12696: sourced facts only. name: "SY-12696, a novel and potent MALT1 protease inhibitor, for the treatment of B-cell lymphomas" [DOI:10.1158/1538-7445.am2025-3034]; target: "SY-12696, a novel and potent MALT1 protease inhibitor, for the treatment of B-cell lymphomas" [DOI:10.1158/1538-7445.am2025-3034]; developer: "Shouyao Holdings (Beijing) Co., Ltd, Beijing, China." [DOI:10.1158/1538-7445.am2025-3034]; modality: "SY-12696 was identified as a novel, potent and small molecular MALT1 inhibitor, it showed excellent potency on MALT1 protease activity both in biochemical and in cellular assays with nanomolar IC50s." [DOI:10.1158/1538-7445.am2025-3034]

02

Targets

MALT1 (Mucosa-associated lymphoid tissue lymphoma translocation protein 1)

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