Drug intelligence / Profile preview

SYD5115

Development stage
Unknown
Lead developer
Byondis
Modality
Small Molecules
01

Overview

SYD5115: sourced facts only. name: "In this paper, we describe the discovery of SYD5115 (67), a novel small molecule TSH-R antagonist with nanomolar potency." [PMID:37001244]; target: "In this paper, we describe the discovery of SYD5115 (67), a novel small molecule TSH-R antagonist with nanomolar potency." [PMID:37001244]; developer: "Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands." [PMID:37001244]; modality: "In this paper, we describe the discovery of SYD5115 (67), a novel small molecule TSH-R antagonist with nanomolar potency." [PMID:37001244]; stage: "SYD5115 also blocks stimulating antibody induced synthesis of the thyroid hormone thyroxine (T4) in vivo, after a single oral dose." [PMID:37001244]

02

Targets

TSHR (Thyroid-stimulating hormone receptor)

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