Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
SYH2083
- Development stage
- Phase 1
- Lead developer
- Shanghai Yishi Pharmaceutical Technology
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
SYH2083 is a small-molecule ophthalmic topical formulation (eye drops) developed by CSPC Pharmaceutical Group (via its subsidiary Shanghai Yishi Pharmaceutical Technology) for the treatment of ocular surface inflammatory diseases, primarily dry eye disease. It acts as an immunomodulator by reducing the adhesion and activation of T lymphocytes, thereby lowering pro-inflammatory signaling on the ocular surface. By targeting the T-cell adhesion-activation axis, SYH2083 aims to interrupt the upstream inflammatory cascade that drives dry eye disease and other ocular surface conditions, such as allergic conjunctivitis, offering a potential rapid-onset alternative to existing therapies like cyclosporine.
- Other names
- SYH2083 eye dropsSYH-2083 eye dropsSYH 2083 eye dropsSYH2083 ophthalmic solutionSYH-2083 ophthalmic solutionSYH 2083 ophthalmic solution
02
Targets
ICAM1 (Intercellular Adhesion Molecule 1)LFA-1 (Integrin αLβ2)
Beyond the preview
Go deeper on SYH2083.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on SYH2083.