Drug intelligence / Profile preview

SYH9089

Development stage
Phase 1
Lead developer
CSPC Ouyi Pharmaceutical
Modality
Small Molecules
Administration
Local
01

Overview

SYH9089 is an investigational long-acting local anesthetic injection developed by CSPC Ouyi Pharmaceutical Co., Ltd. for the management of postoperative pain. It is designed to provide prolonged analgesia at the surgical site, potentially reducing the requirement for systemic opioids. The drug is typically administered via infiltration into the surgical incision wound before closure. SYH9089 is currently being evaluated in Phase I clinical trials to assess its safety, pharmacokinetics, and efficacy in patients undergoing abdominal surgery, where it is compared against standard treatments like ropivacaine hydrochloride and placebo. It is likely a sustained-release formulation, such as a liposomal suspension, of the amide-type local anesthetic bupivacaine.

Other names
SYH9089 injectionSYH-9089 injectionSYH 9089 injection
02

Targets

NaV (Voltage-gated sodium channels)

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