Drug intelligence / Profile preview

SYHX2008

Development stage
Phase 3
Lead developer
CSPC ZhongQi Pharmaceutical Technology
Modality
Peptides
Administration
Subcutaneous
01

Overview

SYHX2008 is a long-acting injectable formulation of octreotide under development for the treatment of acromegaly and gastroenteropancreatic neuroendocrine tumors (GEP-NET). Octreotide is a synthetic somatostatin analog that inhibits the secretion of several hormones, including growth hormone and serotonin, by binding to somatostatin receptors. SYHX2008 is being developed as an alternative to existing long-acting octreotide formulations such as Sandostatin LAR. The drug is currently in phase 2 clinical trials for GEP-NET and has also been studied in phase 1 trials in healthy volunteers[1][2][6][7][9].

Other names
octreotide long-acting injection (investigational name)
02

Targets

SSTR1 (Somatostatin Receptor Type 1)SSTR5 (Somatostatin receptor 5)SSTR2 (Somatostatin receptor type 2)SSTR4 (Somatostatin receptor 4)SSTR3 (Somatostatin receptor 3)

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