Drug intelligence / Profile preview

Symbioflor 1

Development stage
Unknown
Lead developer
Symbiopharm
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Symbioflor 1 is a licensed probiotic medicinal product containing live *Enterococcus faecalis* bacteria (specifically strain DSM 16440). Developed by SymbioPharm (part of the Symbio Herborn Group), it is primarily indicated for the treatment of recurrent respiratory infections, including chronic sinusitis and bronchitis. The drug functions as an immunomodulator; the live bacteria interact with the gut-associated lymphoid tissue (GALT), which in turn stimulates the systemic immune response and enhances mucosal immunity in the respiratory tract. It is typically administered as oral drops and is recognized as a medicinal product in Germany rather than a simple dietary supplement.

Brand names
Symbioflor 1Symbioflor1Symbioflor-1
Other names
Enterococcus faecalis DSM 16440

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