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synthetic bear bile powder
- Development stage
- Unknown
- Lead developer
- Institute of Materia Medica, Chinese Academy of Medical Sciences
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Synthetic bear bile powder is a chemically synthesized pharmaceutical product developed by the Institute of Materia Medica, Chinese Academy of Medical Sciences, as a sustainable and ethical alternative to natural bear bile (Xiongdan). It is designed to mimic the complex chemical profile of natural bear bile, typically containing a standardized mixture of bile acids such as tauroursodeoxycholic acid (TUDCA), ursodeoxycholic acid (UDCA), cholic acid, and chenodeoxycholic acid, along with other components like bilirubin and cholesterol. The drug is intended to provide the same therapeutic benefits as natural bear bile, which is traditionally used in Chinese medicine for its anti-inflammatory, anti-convulsant, and hepatoprotective properties. Clinical development has focused on evaluating its safety and efficacy for indications including convulsions, ocular pain, and pharyngitis.
- Brand names
- Ren'gong Xiongdan Fen
- Other names
- synthetic bear bileHecheng Xiongdan Fen
02
Targets
NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)GPBAR1CHRM2 (Muscarinic acetylcholine receptor M2)
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