Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
synthetic bear bile powder
- Development stage
- Phase 1
- Lead developer
- Institute of Materia Medica, Chinese Academy of Medical Sciences
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Synthetic bear bile powder is a chemically synthesized pharmaceutical product developed by the Institute of Materia Medica, Chinese Academy of Medical Sciences, as a sustainable and ethical alternative to natural bear bile (Xiongdan). It is designed to mimic the complex chemical profile of natural bear bile, typically containing a standardized mixture of bile acids such as tauroursodeoxycholic acid (TUDCA), ursodeoxycholic acid (UDCA), cholic acid, and chenodeoxycholic acid, along with other components like bilirubin and cholesterol. The drug is intended to provide the same therapeutic benefits as natural bear bile, which is traditionally used in Chinese medicine for its anti-inflammatory, anti-convulsant, and hepatoprotective properties. Clinical development has focused on evaluating its safety and efficacy for indications including convulsions, ocular pain, and pharyngitis.
- Brand names
- Ren'gong Xiongdan Fen
- Other names
- synthetic bear bileHecheng Xiongdan Fen
02
Targets
FXR (Farnesoid x-activated receptor)GPBAR1CHRM2 (Muscarinic acetylcholine receptor M2)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)BAR (Bile acid receptor)
Beyond the preview
Go deeper on synthetic bear bile powder.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on synthetic bear bile powder.