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T-Boost
- Development stage
- Preclinical
- Lead developer
- Sakura
- Modality
- CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, TCR-Engineered T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
- Administration
- Intravenous
01
Overview
T-Boost is a proprietary cell therapy platform developed by Sakura Bio designed to enhance the therapeutic potential of immune cells, including T cells and natural killer (NK) cells. The technology focuses on reprogramming these cells to improve their potency, persistence, and resilience within the immunosuppressive tumor microenvironment (TME). T-Boost is engineered to be compatible with various cell therapy modalities such as CAR-T, TCR-T, CAR-NK, and Tumor-Infiltrating Lymphocytes (TILs). By optimizing the metabolic and functional state of the cells, the platform aims to overcome common limitations in treating both solid and hematologic malignancies.
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