Drug intelligence / Profile preview

t-RSV Lycosome

Development stage
Unknown
Lead developer
Lycotec
Modality
Small Molecules, Nanoparticles → Drug Delivery Systems
Administration
Oral
01

Overview

t-RSV Lycosome is a **Lycosome microencapsulated oral formulation of trans-resveratrol** developed by **Lycotec** for **diabetic foot ulcer** in patients with type 2 diabetes. The product is a **small molecule** polyphenolic formulation designed to improve the gastrointestinal stability and systemic bioavailability of trans-resveratrol through Lycotec's lycosome delivery technology. Its proposed pharmacology is centered on **Sirtuin 1 activation** and downstream metabolic, microcirculatory, anti-inflammatory, and tissue-repair effects, with reported reductions in fibrinogen and improvements in ulcer healing parameters. In the described placebo-controlled, examiner-blinded pilot study, oral dosing at 50 mg twice daily for 60 days was associated with markedly greater diabetic foot ulcer closure than placebo. Lycotec's pipeline identifies this program as being in **Phase 2** development for diabetic foot ulcer.

Other names
trans-resveratrol lycosomelycosome-formulated trans-resveratrolmicroencapsulated trans-resveratrol
02

Targets

SIRT1 (NAD-dependent protein deacetylase sirtuin-1)

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