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TACE + sintilimab + bevacizumab
- Development stage
- Preclinical
- Lead developer
- Innovent Biologics
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intra-arterial, Intravenous
01
Overview
A combination therapy consisting of transarterial chemoembolization (TACE) procedure with sintilimab (PD-1 inhibitor) and bevacizumab (anti-VEGF monoclonal antibody). This regimen combines local therapy (TACE) with immunotherapy and anti-angiogenic therapy to treat cancer, likely hepatocellular carcinoma.
02
Targets
VEGFA (Vascular endothelial growth factor A)PDCD1 (Programmed cell death protein 1 receptor)
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