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tadalafil + dapoxetine
- Development stage
- Phase 4
- Lead developer
- Centurion Lab
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Tadalafil + dapoxetine is a fixed-dose combination of two small molecule drugs used primarily in men for the treatment of erectile dysfunction (ED) and premature ejaculation (PE). Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor that works by increasing blood flow to the penis, facilitating erection during sexual stimulation. Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels in nerves, improving control over ejaculation and prolonging intravaginal ejaculatory latency time. The combination addresses both ED and PE simultaneously, offering dual benefits for men experiencing both conditions[2][4][5][8][10].
- Brand names
- DuraplusTazzle DDejac-TED Save PlusEdrive-TDTadawin DMatfil DCorectil XPEdup DE
- Other names
- tadalafil and dapoxetine combination
02
Targets
PDE5 (Phosphodiesterase 5A)SERT (Sodium-dependent serotonin transporter)
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