Drug intelligence / Profile preview

tadalafil + dapoxetine

Development stage
Unknown
Lead developer
Centurion Lab
Modality
Small Molecules
Administration
Oral
01

Overview

Tadalafil + dapoxetine is a fixed-dose combination of two small molecule drugs used primarily in men for the treatment of erectile dysfunction (ED) and premature ejaculation (PE). Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor that works by increasing blood flow to the penis, facilitating erection during sexual stimulation. Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels in nerves, improving control over ejaculation and prolonging intravaginal ejaculatory latency time. The combination addresses both ED and PE simultaneously, offering dual benefits for men experiencing both conditions[2][4][5][8][10].

Brand names
DuraplusTazzle DDejac-TED Save PlusEdrive-TDTadawin DMatfil DCorectil XPEdup DE
Other names
tadalafil and dapoxetine combination
02

Targets

PDE5A (Cyclic GMP-specific phosphodiesterase 5A)SERT (Sodium-dependent serotonin transporter)

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