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Taisho Pharma HPSE1 compound 4e
- Development stage
- Unknown
- Lead developer
- Taisho Pharmaceutical
01
Overview
Taisho Pharma HPSE1 compound 4e: sourced facts only. name: "A structure-based lead optimization of 2 using X-ray co-crystal structure analysis and fragment molecular orbital calculation resulted in 4e, which showed a more than 7-fold increase in HPSE1 inhibitory activity." [PMID:37660465]; target: "A structure-based lead optimization of 2 using X-ray co-crystal structure analysis and fragment molecular orbital calculation resulted in 4e, which showed a more than 7-fold increase in HPSE1 inhibitory activity." [PMID:37660465]; developer: "Medicinal Chemistry Laboratories, Taisho Pharmaceutical Co., Ltd., 1-403 Yoshino-cho, Kita-ku, Saitama 331-9530, Japan." [PMID:37660465]
02
Targets
HPSE (Heparanase)
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