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Takzema
- Development stage
- Phase 2
- Lead developer
- Charak
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral, Topical
01
Overview
Takzema is a proprietary, non-steroidal polyherbal Ayurvedic formulation developed and manufactured by Charak. Available as both a topical ointment and oral tablets, Takzema is indicated for the management of eczema (atopic dermatitis), contact dermatitis, and allergic dermatitis. The formulation contains a synergistic blend of traditional herbs and minerals, including Gandhak Rasayan (purified sulphur), Vang Bhasma (calcined tin), Triphala, Guduchi (*Tinospora cordifolia*), Daruharidra (*Berberis aristata*), Manjishtha (*Rubia cordifolia*), Haridra (*Curcuma longa*), and Neem (*Melia azadirachta*). These components work together to modulate immune and inflammatory responses, suppress pro-inflammatory cytokines, protect keratinocytes, and strengthen the epidermal barrier, thereby alleviating symptoms such as dryness, itching, erythema, and skin irritation.
- Brand names
- Takzema
- Other names
- Takzema OintmentTakzema TabletTakzema Tablets
02
Targets
COX15-LOX (Lysyl Oxidase)
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