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Tamaril
- Development stage
- Phase 3
- Lead developer
- Marjan
- Administration
- Oral
01
Overview
**Tamaril** is a Brazilian oral herbal medicinal laxative manufactured by Marjan. It is a fixed botanical preparation containing senna (*Senna alexandrina*) leaf powder or extract, together with preparations of *Cassia fistula*, *Tamarindus indica*, *Coriandrum sativum*, and *Periandra mediterranea*. Senna-derived sennosides provide the principal stimulant-laxative activity by increasing colonic peristalsis and promoting stool softening; the other plant components contribute laxative, antispasmodic, and supportive gastrointestinal effects. Tamaril is indicated to regulate bowel function and treat constipation, including functional intestinal constipation.
- Brand names
- Tamaril
- Other names
- Senna alexandrina and associationsSenna alexandrina + Cassia fistula + Tamarindus indica + Coriandrum sativum + Periandra mediterranea
02
Targets
HRH1 (Histamine H1 Receptor)PTGER (Prostaglandin E2 receptor)ATP1A (Sodium/potassium-transporting ATPase)
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