Drug intelligence / Profile preview

Tamsquare-D

Development stage
Unknown
Lead developer
Golden Square Lab
Modality
Small Molecules
Administration
Oral
01

Overview

**Tamsquare-D** is an oral fixed-dose combination product marketed by **Golden Square** in India for **benign prostatic hyperplasia**. It contains **tamsulosin 0.4 mg** and **dutasteride 0.5 mg**, both **small molecules**. Tamsulosin is an **alpha-1 adrenergic receptor antagonist** that relaxes smooth muscle in the prostate and bladder neck to improve urinary flow, while dutasteride is a **5-alpha-reductase inhibitor** that lowers dihydrotestosterone synthesis and helps reduce prostate volume. The product is positioned as a symptomatic and disease-modifying combination treatment for men with enlarged prostate associated lower urinary tract symptoms.

Brand names
Tamsquare-D
Other names
tamsulosin + dutasteride
02

Targets

ADRA1A (α1A)SRD5A1 (Steroid 5-alpha-reductase type 1)ADRA1D (α1D)SRD5A2 (Steroid 5-alpha-reductase type II)

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