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tamsulosin + dutasteride
- Development stage
- Unknown
- Lead developer
- Cam Neuro Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**URICAM-D** is an oral fixed-dose combination of **tamsulosin hydrochloride** and **dutasteride** developed by Cam Neuro Pharma for **benign prostatic hyperplasia**. Tamsulosin is a selective alpha-1 adrenergic receptor antagonist, with functional selectivity for alpha-1A receptors in prostatic and urethral smooth muscle, which improves urinary flow by reducing smooth-muscle tone. Dutasteride inhibits type 1 and type 2 5-alpha-reductase, lowering dihydrotestosterone production and reducing prostate volume over time. The combination addresses both rapid relief of lower urinary tract symptoms and the androgen-driven progression of prostate enlargement.
- Brand names
- URICAM-D
- Other names
- tamsulosin hydrochloride + dutasterideUricam D
02
Targets
ADRA1A (α1A)ADRA1D (α1D)SRD5A2 (Steroid 5-alpha-reductase type II)SRD5A1 (Steroid 5-alpha-reductase type 1)
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