Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
tamsulosin + silodosin
- Development stage
- Phase 4
- Lead developer
- Mansoura University
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Tamsulosin + silodosin is a combination regimen consisting of two selective alpha-1 adrenergic receptor antagonists (alpha-1 blockers) being investigated for the treatment of lower urinary tract symptoms (LUTS) and acute urinary retention (AUR) associated with benign prostatic hyperplasia (BPH). Tamsulosin and silodosin both work by blocking alpha-1 adrenergic receptors in the prostate and bladder neck, which relaxes smooth muscle and improves urinary flow. Silodosin is highly selective for the alpha-1A receptor subtype, whereas tamsulosin exhibits selectivity for both alpha-1A and alpha-1D subtypes. This combination is being evaluated in clinical trials, such as those conducted by Mansoura University, to determine if dual alpha-1 blockade provides superior therapeutic efficacy compared to standard monotherapy.
- Other names
- silodosin + tamsulosintamsulosin and silodosin
02
Targets
ADRA1A (α1A)ADRA1B (α1B)ADRA1D (α1D)
Beyond the preview
Go deeper on tamsulosin + silodosin.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on tamsulosin + silodosin.