tanacetum cinerariifolium flower extract

Tanacetum cinerariifolium flower extract is an allergenic extract derived from the Dalmatian pyrethrum plant, used primarily as a diagnostic agent in allergy testing. Approved in the United States in 1965 under BLA 103753, the extract is employed in skin prick or intradermal testing to identify individuals with hypersensitivity to pyrethrum or chrysanthemum allergens. The diagnostic procedure relies on the extract's ability to cross-link allergen-specific IgE on mast cells, inducing a localized inflammatory response (wheal and flare) in sensitive patients. This testing is clinically significant for diagnosing the cause of allergic dermatitis, rhinitis, and asthma in individuals exposed to pyrethrum-containing products or the plant itself.

Other names

Tanacetum cinerariifolium flowerPyrethrum extractDalmatian pyrethrum extractChrysanthemum cinerariifolium flower extract