Drug intelligence / Profile preview

tanacetum sinaicum essential oil

Development stage: Preclinical
Administration: Oral, Topical, Inhalation

Overview

Tanacetum sinaicum essential oil is a botanical extract derived from the Sinai Tansy plant (*Tanacetum sinaicum*) through hydrodistillation. Characterized by high concentrations of chrysanthenyl acetate, thujone, and verbenol, the oil exhibits multi-faceted biological activities including antiviral, antiproliferative, and anti-metastatic effects. In preclinical in vitro models, it has demonstrated significant efficacy in inhibiting the replication of human papillomavirus (HPV) types 16 and 18 and suppressing the growth of HeLa (cervical cancer) and MCF-7 (breast adenocarcinoma) cell lines. The oil's mechanism of action involves the induction of autophagy and dose-dependent genotoxicity, leading to DNA damage and programmed cell death in malignant cells.

Other names: Tanacetum sinaicum EOessential oil of Tanacetum sinaicum

Targets

DNA

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