Drug intelligence / Profile preview

Tangerine

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral, Topical, Aromatherapy
01

Overview

Tangerine refers to the fruit *Citrus reticulata* and its various derivatives, such as peel, juice, essential oils, and seeds. These components are utilized across a range of applications, including as flavors, ingredients in hygiene products, and as active components in functional foods, traditional medicines, and dietary supplements. Tangerine derivatives are investigated for their potential therapeutic effects, such as alleviating morning sickness, contributing to prostate cancer treatment, promoting skin health, and ameliorating metabolic syndrome. They are also a source of compounds like lycopene and carbon dots, and are extensively used in Traditional Chinese Medicine for various conditions.

Other names
Citri Reticulatae PericarpiumChen PiQing Pi
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)JNK (Mitogen-activated protein kinase kinase kinase family)NF-κBRK (Ribokinase)IL1B (Interleukin-1 beta)IL-6 (Interleukin 6)MMP9 (Matrix metalloproteinase-9)NO2- (Nitrite)NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)PPARG (Peroxisome proliferator-activated receptor gamma)PIK3CA (Phosphoinositide 3-kinase alpha)TP53 (Cellular Tumor Antigen p53 R175H)GPBAR1TNFA (Tumor necrosis factor alpha (soluble))

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