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tangminling
- Development stage
- Phase 3
- Lead developer
- Guang'anmen Hospital
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Tangminling is a traditional Chinese herbal medicine composed of ten Chinese herbs. It is primarily prescribed for the management of type 2 diabetes mellitus (T2DM) in mainland China. Clinical studies have shown that tangminling can reduce glucose levels and body weight and may improve β-cell function in T2DM patients. The mechanism of action is not fully elucidated but appears to involve modulation of glucose metabolism and possibly enhancement of pancreatic β-cell function[1][10]. The drug was initially developed by Guang'anmen Hospital, China Academy of Chinese Medical Sciences[2].
- Brand names
- Tang-min-ling pills
- Other names
- Tangminling pillTang-min-ling-wanTM81TM-81TM 81
02
Targets
AMPK (Adenosine monophosphate–activated protein kinase)SLC2A4 (Solute carrier family 2 facilitated glucose transporter member 4)
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