Drug intelligence / Profile preview

Tangzu Granule

Development stage
Preclinical
Lead developer
Hospital of Chengdu University of Traditional Chinese Medicine
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Tangzu Granule is a Traditional Chinese Medicine (TCM) formulation developed by the Hospital of Chengdu University of TCM for the prevention and treatment of high-risk diabetic foot in patients with type 2 diabetes mellitus. The medication is designed for dual administration, involving both oral intake and external (topical) application. It aims to provide a multi-targeted therapeutic approach to manage the complications of diabetic foot, focusing on improving local microcirculation and supporting wound healing. As a hospital-developed preparation, it is currently undergoing clinical evaluation to establish a standardized evidence base for its efficacy and safety in managing diabetic complications.

Other names
糖足颗粒
02

Targets

P2RX7 (P2X purinoceptor 7)CASP1 (Caspase-1)GSDMD (Gasdermin D)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

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