Drug intelligence / Profile preview

TATX-03E

Development stage
Preclinical
Lead developer
ImmunoPrecise Antibodies
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

TATX-03E is a high-concentration, alternative formulation of the PolyTope® TATX-03 antibody cocktail developed for the treatment and prevention of COVID-19. It is designed to be easily self-administered outside healthcare settings, enabling rapid deployment and field use, particularly for immunocompromised individuals who may require ongoing access to antibody therapies or prophylaxis. The original PolyTope® TATX-03 consists of multiple synergistic human IgG1 monoclonal antibodies targeting diverse epitopes on SARS-CoV-2, aiming to provide broad neutralization across variants and reduce mutagenic escape risk. Preclinical studies have demonstrated strong efficacy in both therapeutic and prophylactic models against SARS-CoV-2 infection[1][2][3].

Brand names
TATX-03ETATX03ETATX 03E
Other names
PolyTope TATX-03E
02

Targets

SARS-CoV-2 spike

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