Drug intelligence / Profile preview

TATX-21

Development stage
Preclinical
Lead developer
ImmunoPrecise Antibodies
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

TATX-21 is a **preclinical rabbit-derived anti-ALK1 monoclonal antibody program** being developed by ImmunoPrecise Antibodies through its Talem Therapeutics subsidiary. The program comprises a diverse panel of monoclonal antibodies generated from rabbit B cells using single B cell discovery technology and is directed against **activin receptor-like kinase 1**. Available sources describe TATX-21 as targeting ALK1 and in at least one source as an **ALK1 agonist**; it has also been associated with **anti-angiogenic effects** and proposed development in **solid tumors**, while broader anti-ALK1 antibody research cited alongside the program discusses potential use in **atherosclerotic cardiovascular disease** through inhibition of LDL-mediated transcytosis. The asset remains investigational with no identified brand name and no disclosed clinical-stage administration or formulation details.

Other names
anti-ALK1 rabbit-derived monoclonal antibody panelanti-ALK-1 rabbit-derived monoclonal antibody panelanti-ALK 1 rabbit-derived monoclonal antibody panel
02

Targets

ACVRL1 (Activin receptor-like kinase 1)

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