Drug intelligence / Profile preview

taurine

Development stage
Phase 4
Lead developer
Taisho Pharmaceutical
Modality
Small Molecules
Administration
Oral, Intravenous
01

Overview

Taurine is a naturally occurring sulfur-containing amino acid (specifically a sulfonic acid) that is not incorporated into proteins but plays critical roles in various physiological processes. It is primarily known for its role in bile acid conjugation, which is essential for lipid digestion and the regulation of cholesterol levels. Beyond its metabolic functions, taurine acts as an osmolyte, helping to maintain cellular volume and fluid balance. It also exhibits antioxidant properties and modulates calcium signaling in cardiac and skeletal muscles. In clinical practice, taurine has been used to treat congestive heart failure, particularly in Japan, and is investigated for its potential benefits in metabolic disorders like hypercholesterolemia and diabetes. It is also a common ingredient in energy drinks and dietary supplements.

Brand names
Taurosel
Other names
2-aminoethanesulfonic acidL-taurine牛磺酸
02

Targets

BAAT (Bile acid-CoA:amino acid N-acyltransferase)CYP2E1

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