Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
taurine + sodium chloride
- Development stage
- Phase 2
- Lead developer
- Beijing Neurosurgical Institute
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Taurine + sodium chloride is an intravenous neuroprotective formulation developed by the Beijing Neurosurgical Institute for the treatment of acute ischemic stroke. Taurine is a semi-essential sulfur-containing amino acid that functions as an endogenous inhibitory neurotransmitter and a potent antioxidant. In the context of stroke, it acts as an agonist at GABA-A and glycine receptors, helping to counteract glutamate-induced excitotoxicity. Additionally, taurine serves as a scavenger for reactive oxygen species, stabilizes mitochondrial membranes, and modulates intracellular calcium levels to prevent neuronal apoptosis. The sodium chloride component serves as an isotonic vehicle for delivery. This therapy is currently being evaluated in Phase 2 clinical trials to assess its efficacy in improving functional recovery and reducing infarct volume in patients following an acute ischemic event.
- Other names
- Taurine InjectionTaurine in Normal Saline
02
Targets
GABRR (GABA-A receptor subunit rho)Glycine receptorGABA-B (Gamma-aminobutyric acid receptor type B)
Beyond the preview
Go deeper on taurine + sodium chloride.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on taurine + sodium chloride.