Tavanic

Tavanic is a brand name for levofloxacin, a third-generation fluoroquinolone antibiotic. It is the S-enantiomer of the racemic mixture ofloxacin and possesses broad-spectrum antibacterial activity against a wide range of Gram-positive and Gram-negative pathogens, including *Streptococcus pneumoniae*, *Haemophilus influenzae*, and atypical organisms like *Mycoplasma pneumoniae*. Levofloxacin exerts its bactericidal effect by inhibiting bacterial DNA gyrase and topoisomerase IV, which are essential enzymes for DNA replication, transcription, repair, and recombination. In the clinical context provided, Tavanic is utilized as a standard-of-care reference comparator in Phase 3 trials for new anti-infective agents, such as nemonoxacin, specifically for the treatment of community-acquired pneumonia (CAP). R-Pharm serves as a key developer and distributor of the product in specific regions, including Russia and the CIS.

Brand names

Tavanic

Other names

levofloxacinL-ofloxacin