Drug intelligence / Profile preview

TB-006

Development stage
Preclinical
Lead developer
TrueBinding
Modality
CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

TB-006 is an investigational, universal off-the-shelf chimeric antigen receptor (CAR) cell therapy being developed by ThinkingBiomed for the treatment of solid tumors. It utilizes a proprietary "INK" cell platform, referred to as CAR-INK, which is a specialized variant of natural killer (NK) cell therapy. The development of TB-006 involves ThinkingBiomed's organoid high-throughput drug screening platform to validate efficacy against various solid tumor types, which may include thoracic, digestive, urinary, and reproductive system cancers. As of early 2024, the program is in the early research and preclinical validation stage, and its specific molecular targets have not been publicly disclosed.

Other names
TB-006 CAR-INK cell therapyTB006 CAR-INK cell therapyTB 006 CAR-INK cell therapy
02

Targets

LGALS3 (Galectin-3)

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