Drug intelligence / Profile preview

TC-13-183

Development stage
Unknown
Lead developer
Chongqing Precision Biotech Co., Ltd
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intraperitoneal
01

Overview

TC-13-183 is an autologous chimeric antigen receptor T-cell (CAR-T) therapy developed by Chongqing Precision Biotechnology. It is designed to target carcinoembryonic antigen (CEA) and is developed using the company's proprietary ToughCAR® platform, which utilizes a metabolically optimized rapid manufacturing process. This platform allows for faster preparation and a therapeutic dose that is approximately one-tenth of conventional CAR-T therapies, enhancing CAR-T cell function and suitability for solid tumors. TC-13-183 is administered via local intraperitoneal injection to treat CEA-positive advanced peritoneal metastatic colorectal cancer.

Other names
TC-13-183细胞制剂
02

Targets

CEACAM5 (Carcinoembryonic antigen related cell adhesion molecule 5)

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