Drug intelligence / Profile preview

TC091

Development stage
Preclinical
Lead developer
TiCARos Therapeutics
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

TC091 is a chimeric antigen receptor T-cell (CAR-T) therapy developed by Ticaros, designed to target solid tumors. It utilizes Ticaros' proprietary CLIP CAR (Clamping-based Immune Synapse Potentiating CAR) technology, which aims to enhance both tumor-killing capability and stability. The drug is currently in preclinical development, with an Investigational New Drug (IND) submission planned for July 2026, and is being developed for various solid tumor indications, including liver, gallbladder, and pancreatic cancers.

02

Targets

MUC1 (Mucin-1 Antigen)

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