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Tears Again
- Development stage
- Unknown
- Lead developer
- Optima Pharmazeutische
- Administration
- Ophthalmic
01
Overview
**Tears Again** is a preservative-free liposomal eye spray marketed as a medical device for symptomatic treatment of dry eye disease, particularly evaporative dry eye associated with tear-film lipid-layer deficiency. The spray is applied to closed eyelids; phospholipid liposomes distribute onto the ocular surface during blinking and stabilize the tear film's protective lipid layer, reducing tear evaporation and improving ocular-surface moisturization. Clinical studies have reported improvement in dry-eye symptoms and non-invasive tear break-up time, with favorable handling and tolerability assessments. Tears Again is manufactured and marketed by Optima Pharma and has also been clinically sponsored in Israel by Trima Israel Pharmaceutical Products.
- Brand names
- Optrex ActiMistTears Again
- Other names
- Tears Again Eye SprayTears Again liposomal sprayTears Again Original
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